C-Trap Dymo Short Tether Package Upgrade

The University at Buffalo intends to make an award under our discretionary authority, pursuant to NYS Education Law §355 (5) (a), which is up to $125,000, for a C-Trap Dymo Short Tether Package upgrade. The Short Tether upgrade must include the minimum requirements and be compatible with the existing C-Trap Dymo 300 Optical Tweezer-Fluorescence Microscope system and Bluelake software. A sealed bid will not be held. If you are interested in providing a proposal for the above commodity or a university approved equivalent, you must contact the appropriately designated Campus contact in this advertisement within 15 business days of this Advertisement Notice.

 Package Upgrade Minimum Requirements:

•  Active Trap Stabilization
  • Stabilizes distance of two optical traps for long-term observations
  • Compared to a non-stabilized setup, drift is reduced by a factor 2 to 4
  • Drift level of <0.5nm/10minutes1x and 2.8x magnification changer positions
• Nanostage 3D
  • Piezo-controlled
  • Conduction of single-molecule force spectroscopy surface assays
  • Maintenance of constant force in the x- and y-direction
  • Integration of z-movement in the confocal scanning software for 3D enabling
• Active Force Calibration
  • Sinusoidal force application to trapped beads to minimize variability
• Advanced Piezo Trap Tracking
  • Fast bead position readout up to 78 KHz
  • Independent molecular tether length
  • High temporal resolution
• Baseline Correction
  • Recording of crosstalk for signal-to-background ratio optimization

• Shipping, Handling and Insurance charges
• Lead Time four to eight (4-8) weeks